Nonstop flights from Tampa to Louisville

2 airlines fly this route, with up to 2 flights a day.

TPATampa International

729 mi · 9 flights a week

SDFLouisville Muhammad Ali International

TPASDF

When they leave

Tampa time

8:00a1:05pFirst departure 8:00 AM, last 1:05 PM

Four in the morning, 8:00 AM to 11:30 AM, then one afternoon flight at 1:05 PM.

Every flight

Earliest first

8:00 AM→10:05 AMSouthwest AirlinesBoeing 737-700Sun
8:05 AM→10:10 AMSouthwest AirlinesBoeing 737-700Tue, Wed
8:18 AM→10:32 AMBreeze AirwaysAirbus A220-300Thu, Sun
11:30 AM→1:35 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Thu, Fri
1:05 PM→3:10 PMSouthwest AirlinesBoeing 737 MAX 8Sat

Schedules last checked Sep 19, 2026. Times are local.

Flying from Tampa to Louisville

Southwest Airlines flies most often, daily on the Boeing 737 MAX 8 and Boeing 737-700. Breeze Airways flies on Thursdays and Sundays with the Airbus A220-300.

Flights run every day of the week, 2 on Thursdays and Sundays and 1 on the other days. The first arrival in Louisville is at 10:05 AM and the last at 3:10 PM. The flight covers 729 miles.

Flying back, Louisville to Tampa has 9 nonstop flights a week.

Return flights

Louisville to TampaView

Find the cheapest day to fly from Tampa to Louisville.

Schedules as of Oct 9, 2026.