Nonstop flights from Louisville
SDF · Louisville Muhammad Ali International
6 airlines fly nonstop from Louisville to 39 destinations in the United States. The busiest routes are to Chicago (ORD), Atlanta and Dallas (DFW). 2 routes start or resume in the coming months.
Starting soon
- Oklahoma CityFirst flight · Southwest AirlinesFirst flight Oct 16, 2026
- OrlandoFirst flight · Allegiant AirFirst flight Oct 22, 2026
Ending soon
- Gulf ShoresLast flight · Allegiant AirLast flight Nov 1, 2026
Nonstop flights from Louisville within the United States
39- AtlantaATL
Delta Air Lines · 7 to 8 a day6:00a5:50pFirst departure 6:00 AM, last 5:50 PM - BaltimoreBWI
Southwest Airlines · 2 to 3 a day5:40a5:00pFirst departure 5:40 AM, last 5:00 PM - BostonBOS
2 airlines · 2 a day12:54p5:10pFirst departure 12:54 PM, last 5:10 PM - CharlestonCHS
Breeze Airways · 2 a weekUntil Jan 4, 20278:28p8:28pDeparts 8:28 PM - CharlotteCLTAmerican Airlines · 4 to 5 a day6:05a7:12pFirst departure 6:05 AM, last 7:12 PM
- ChicagoMDWMidwaySouthwest Airlines · 2 to 3 a day9:00a7:25pFirst departure 9:00 AM, last 7:25 PM
- ChicagoORDO'Hare
2 airlines · 8 to 9 a day5:10a7:18pFirst departure 5:10 AM, last 7:18 PM - DallasDALLove FieldSouthwest Airlines · Daily7:55a3:50pFirst departure 7:55 AM, last 3:50 PM
- DallasDFWFort WorthAmerican Airlines · 4 to 6 a day7:03a7:03pFirst departure 7:03 AM, last 7:03 PM
- DenverDEN2 airlines · 3 a day8:00a3:25pFirst departure 8:00 AM, last 3:25 PM
- DestinVPS
Allegiant Air · Daily9:30a7:20pFirst departure 9:30 AM, last 7:20 PM - DetroitDTWDelta Air Lines · 3 to 4 a day7:55a5:25pFirst departure 7:55 AM, last 5:25 PM
- Fort LauderdaleFLLAllegiant Air · 6 a week10:39a9:10pFirst departure 10:39 AM, last 9:10 PM
- Fort MyersRSWBreeze Airways · 4 a week9:27p9:27pDeparts 9:27 PM
Show 25 more
- Gulf ShoresGUFAllegiant Air · 2 a weekUntil Nov 15:04p5:04pDeparts 5:04 PM
- HartfordBDLBreeze Airways · 2 a week10:35a10:35aDeparts 10:35 AM
- HoustonHOUWilliam P. HobbySouthwest Airlines · Daily12:40p6:25pFirst departure 12:40 PM, last 6:25 PM
- HoustonIAHGeorge Bush IntercontinentalUnited Airlines · 3 a day7:25a3:35pFirst departure 7:25 AM, last 3:35 PM
- Las VegasLASSouthwest Airlines · Daily6:10a4:50pFirst departure 6:10 AM, last 4:50 PM
- MiamiMIAAmerican Airlines · 1 to 2 a day6:00a6:25aFirst departure 6:00 AM, last 6:25 AM
- MinneapolisMSPDelta Air Lines · 3 to 4 a day6:50a7:54pFirst departure 6:50 AM, last 7:54 PM
- NashvilleBNASouthwest Airlines · 2 a dayUntil Jan 21, 20276:45a4:05pFirst departure 6:45 AM, last 4:05 PM
- New OrleansMSYBreeze Airways · 2 a week11:39a11:39aDeparts 11:39 AM
- New YorkLGADelta Air Lines · 2 to 4 a day6:00a5:59pFirst departure 6:00 AM, last 5:59 PM
- NewarkEWRUnited Airlines · 3 a day6:15a1:08pFirst departure 6:15 AM, last 1:08 PM
- Oklahoma CityOKCSouthwest Airlines · 1 a weekFrom Oct 168:50a8:50aDeparts 8:50 AM
- OrlandoMCOOrlandoSouthwest Airlines · 11 a week6:00a5:50pFirst departure 6:00 AM, last 5:50 PM
- OrlandoSFBSanfordAllegiant Air · 1 a weekFrom Oct 225:19p5:19pDeparts 5:19 PM
- PhiladelphiaPHLAmerican Airlines · 3 a day7:31a6:18pFirst departure 7:31 AM, last 6:18 PM
- PhoenixPHXSouthwest Airlines · Daily11:05a2:35pFirst departure 11:05 AM, last 2:35 PM
- PittsburghPITBreeze Airways · 4 a weekUntil Jan 4, 202710:25a6:55pFirst departure 10:25 AM, last 6:55 PM
- Punta GordaPGDAllegiant Air · 6 a weekUntil Mar 2, 20279:28a6:27pFirst departure 9:28 AM, last 6:27 PM
- RaleighRDUBreeze Airways · 2 a week2:56p2:56pDeparts 2:56 PM
- San FranciscoSFOBreeze Airways · 2 a weekUntil Jan 4, 20279:31a9:31aDeparts 9:31 AM
- SarasotaSRQAllegiant Air · 5 a week5:14p9:26pFirst departure 5:14 PM, last 9:26 PM
- TampaPIESt. Pete-ClearwaterAllegiant Air · 5 a weekUntil Feb 1, 202710:01a3:48pFirst departure 10:01 AM, last 3:48 PM
- TampaTPATampa2 airlines · 1 to 2 a day9:55a4:10pFirst departure 9:55 AM, last 4:10 PM
- WashingtonDCARonald Reagan Washington NationalAmerican Airlines · 2 to 3 a day6:11a3:21pFirst departure 6:11 AM, last 3:21 PM
- WashingtonIADDullesUnited Airlines · 2 to 3 a day6:00a1:56pFirst departure 6:00 AM, last 1:56 PM
- Gulf ShoresGUF
Airlines at Louisville
6
See everywhere you can fly from Louisville on the dates you're free.
Schedules as of Oct 9, 2026.