Nonstop flights from Orlando to Louisville

2 airlines fly from 2 Orlando airports (MCO and SFB) to Louisville (SDF), with up to 3 flights a day.

MCOSDF

Routes

2 airport pairs

MCO to SDFOrlando to Louisville Muhammad Ali1 to 3 a day
SFB to SDFOrlando Sanford to Louisville Muhammad Ali1 a week

When they leave

Orlando time

8:50a7:45pFirst departure 8:50 AM, last 7:45 PM

Two in the morning, 8:50 AM to 9:00 AM, then two in the afternoon, 2:10 PM to 2:25 PM, then one evening flight at 7:45 PM.

Every flight

Earliest first

8:50 AM→11:00 AMMCO to SDFSouthwest AirlinesBoeing 737-700Sun
9:00 AM→11:10 AMMCO to SDFSouthwest AirlinesBoeing 737 MAX 8Mon, Thu, Fri
9:00 AM→11:10 AMMCO to SDFSouthwest AirlinesBoeing 737-700Sat
9:00 AM→11:10 AMMCO to SDFSouthwest AirlinesBoeing 737 MAX 8Tue, Wed
2:10 PM→4:15 PMMCO to SDFSouthwest AirlinesBoeing 737Sat
2:25 PM→4:29 PMSFB to SDFAllegiant AirFrom Oct 18Airbus A320Sun
7:45 PM→9:55 PMMCO to SDFSouthwest AirlinesBoeing 737-700Mon, Thu, Fri, Sat, Sun

Schedules last checked Sep 22, 2026. Times are local.

Flying from Orlando to Louisville

Southwest Airlines flies most often, 1 to 3 times a day on the Boeing 737-700, Boeing 737 MAX 8 and Boeing 737. Allegiant Air flies on Sundays with the Airbus A320.

Flights run every day of the week, from 1 on Tuesdays and Wednesdays to 3 on Saturdays and Sundays. The first arrival in Louisville is at 11:00 AM and the last at 9:55 PM.

MCO to SDF is the busiest airport pair, with 13 flights a week, then SFB to SDF with 1.

On SFB to SDF, Allegiant Air starts on Oct 18.

Flying back, Louisville to Orlando has 12 nonstop flights a week.

Return flights

Louisville to OrlandoView

Find the cheapest day to fly from Orlando to Louisville.

Schedules as of Oct 9, 2026.