Nonstop flights from Louisville to Charlotte
American Airlines flies this route 4 to 5 times a day.
SDFLouisville Muhammad Ali International
336 mi · 34 flights a week
CLTCharlotte Douglas International
When they leave
Louisville time6:05a7:12pFirst departure 6:05 AM, last 7:12 PM
Three in the morning, 6:05 AM to 11:10 AM, then two in the afternoon, 2:36 PM to 4:55 PM, then one evening flight at 7:12 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Louisville to Charlotte
American Airlines is the only airline flying nonstop from Louisville to Charlotte, 4 to 5 times a day on the Airbus A320, CRJ 900 and CRJ 700.
There are 4 or 5 flights every day of the week. The first arrival in Charlotte is at 7:45 AM and the last at 8:49 PM. The flight covers 336 miles.
Flying back, Charlotte to Louisville has 34 nonstop flights a week.
Return flights
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Schedules as of Oct 9, 2026.