Nonstop flights from Charlotte to Louisville
American Airlines flies this route 4 to 5 times a day.
CLTCharlotte Douglas International
336 mi · 34 flights a week
SDFLouisville Muhammad Ali International
When they leave
Charlotte time8:41a9:49pFirst departure 8:41 AM, last 9:49 PM
One morning flight at 8:41 AM, then three in the afternoon, 12:30 PM to 4:33 PM, then two in the evening, 7:55 PM to 9:49 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Charlotte to Louisville
American Airlines is the only airline flying nonstop from Charlotte to Louisville, 4 to 5 times a day on the CRJ 900, Airbus A320 and CRJ 700.
There are 4 or 5 flights every day of the week. The first arrival in Louisville is at 10:18 AM and the last at 11:11 PM. The flight covers 336 miles.
Flying back, Louisville to Charlotte has 34 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Charlotte to Louisville.
Schedules as of Oct 9, 2026.