Nonstop flights from Houston to Louisville
United Airlines flies this route 3 times a day.
IAHHouston George Bush Intercontinental
789 mi · 21 flights a week
SDFLouisville Muhammad Ali International
When they leave
Houston time9:45a6:50pFirst departure 9:45 AM, last 6:50 PM
One morning flight at 9:45 AM, then one afternoon flight at 4:37 PM, then one evening flight at 6:50 PM. Every flight runs daily.
Every flight
Earliest first
Schedules last checked Sep 21, 2026. Times are local.
Flying from Houston to Louisville
United Airlines is the only airline flying nonstop from Houston to Louisville, 3 times a day on the Embraer 175.
The first arrival in Louisville is at 1:07 PM and the last at 10:15 PM. The flight covers 789 miles.
Flying back, Louisville to Houston has 21 nonstop flights a week. William P. Hobby (HOU) also has nonstop flights to Louisville, 7 a week.
Return flights
Every Houston airport
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Find the cheapest day to fly from Houston to Louisville.
Schedules as of Oct 9, 2026.