Nonstop flights from Philadelphia to Louisville
American Airlines flies this route 3 times a day.
PHLPhiladelphia International
575 mi · 21 flights a week
SDFLouisville Muhammad Ali International
When they leave
Philadelphia time9:49a8:40pFirst departure 9:49 AM, last 8:40 PM
One morning flight at 9:49 AM, then one afternoon flight at 3:31 PM, then one evening flight at 8:40 PM. Every flight runs daily.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Philadelphia to Louisville
American Airlines is the only airline flying nonstop from Philadelphia to Louisville, 3 times a day on the Embraer 175 and Embraer ERJ-145.
The first arrival in Louisville is at 12:07 PM and the last at 10:59 PM. The flight covers 575 miles.
Flying back, Louisville to Philadelphia has 21 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Philadelphia to Louisville.
Schedules as of Oct 9, 2026.