Nonstop flights from Minneapolis to Louisville
Delta Air Lines flies this route 3 to 4 times a day.
MSPMinneapolis-Saint Paul International
602 mi · 27 flights a week
SDFLouisville Muhammad Ali International
When they leave
Minneapolis time8:55a8:54pFirst departure 8:55 AM, last 8:54 PM
One morning flight at 8:55 AM, then two in the afternoon, 12:53 PM to 4:17 PM, then one evening flight at 8:54 PM.
Every flight
Earliest first
Schedules last checked Sep 20, 2026. Times are local.
Flying from Minneapolis to Louisville
Delta Air Lines is the only airline flying nonstop from Minneapolis to Louisville, 3 to 4 times a day on the CRJ 700 and CRJ 900.
There are 3 or 4 flights every day of the week. The first arrival in Louisville is at 11:55 AM and the last at 11:56 PM. The flight covers 602 miles.
Flying back, Louisville to Minneapolis has 27 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Minneapolis to Louisville.
Schedules as of Oct 9, 2026.