Nonstop flights from Denver to Louisville
2 airlines fly this route, with up to 3 flights a day.
DENDenver International
1,021 mi · 21 flights a week
SDFLouisville Muhammad Ali International
When they leave
Denver time9:45a5:45pFirst departure 9:45 AM, last 5:45 PM
Two in the morning, 9:45 AM to 11:20 AM, then one afternoon flight at 12:50 PM, then one evening flight at 5:45 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Denver to Louisville
United Airlines flies most often, twice a day on the Airbus A320. Southwest Airlines flies daily on the Boeing 737 MAX 8.
There are 3 flights every day of the week. The first arrival in Louisville is at 2:29 PM and the last at 10:31 PM. The flight covers 1,021 miles.
Flying back, Louisville to Denver has 21 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Denver to Louisville.
Schedules as of Oct 9, 2026.