Nonstop flights from Des Moines
DSM · Des Moines International
6 airlines fly nonstop from Des Moines to 28 destinations in the United States. The busiest routes are to Chicago (ORD), Denver and Dallas. 1 route starts or resumes in the coming months.
Starting soon
- NewarkFirst flight · Allegiant AirFirst flight Nov 20, 2026
Ending soon
- PhiladelphiaLast flight · 2 airlinesLast flight Nov 1, 2026
- BostonLast flight · Allegiant AirLast flight Nov 29, 2026
Nonstop flights from Des Moines within the United States
28- AtlantaATL
Delta Air Lines · 3 to 4 a day5:41a6:37pFirst departure 5:41 AM, last 6:37 PM - AustinAUS
Allegiant Air · 5 a week7:15a8:00aFirst departure 7:15 AM, last 8:00 AM - BostonBOSAllegiant Air · 4 a weekUntil Nov 297:15a7:20aFirst departure 7:15 AM, last 7:20 AM
- CharlotteCLT
American Airlines · 2 to 3 a day8:10a5:10pFirst departure 8:10 AM, last 5:10 PM - ChicagoMDWMidway
Southwest Airlines · 2 a day5:40a3:50pFirst departure 5:40 AM, last 3:50 PM - ChicagoORDO'Hare
2 airlines · 4 to 9 a day6:00a7:49pFirst departure 6:00 AM, last 7:49 PM - DallasDFWAmerican Airlines · 4 a day5:12a7:35pFirst departure 5:12 AM, last 7:35 PM
- DenverDEN
3 airlines · 6 to 8 a day5:45a7:10pFirst departure 5:45 AM, last 7:10 PM - DetroitDTWDelta Air Lines · 3 a day6:00a5:30pFirst departure 6:00 AM, last 5:30 PM
- Fort LauderdaleFLLAllegiant Air · 5 a week9:52a6:17pFirst departure 9:52 AM, last 6:17 PM
- Fort MyersRSWAllegiant Air · 4 a week9:30a3:04pFirst departure 9:30 AM, last 3:04 PM
- Gulf ShoresGUFAllegiant Air · 4 a week8:30a5:23pFirst departure 8:30 AM, last 5:23 PM
- HoustonIAHUnited Airlines · 2 a day6:15a3:02pFirst departure 6:15 AM, last 3:02 PM
- Las VegasLAS2 airlines · 1 to 2 a day12:05p10:06pFirst departure 12:05 PM, last 10:06 PM
Show 14 more
- Los AngelesLAXAmerican Airlines · Daily6:48p6:48pDeparts 6:48 PM
- MiamiMIAAmerican Airlines · 6 a week5:00a6:30aFirst departure 5:00 AM, last 6:30 AM
- MinneapolisMSPDelta Air Lines · 3 to 4 a day6:55a5:56pFirst departure 6:55 AM, last 5:56 PM
- NashvilleBNAAllegiant Air · 6 a week6:25a9:20pFirst departure 6:25 AM, last 9:20 PM
- New YorkLGA2 airlines · 1 to 2 a day7:10a7:15aFirst departure 7:10 AM, last 7:15 AM
- NewarkEWRAllegiant Air · 5 a weekFrom Nov 207:35a7:35aDeparts 7:35 AM
- PhiladelphiaPHL2 airlines · 2 to 3 a dayUntil Nov 15:40a1:55pFirst departure 5:40 AM, last 1:55 PM
- PhoenixAZAMesa GatewayAllegiant Air · Daily8:00a9:10pFirst departure 8:00 AM, last 9:10 PM
- PhoenixPHXSky Harbor2 airlines · 2 to 4 a day5:00a6:29pFirst departure 5:00 AM, last 6:29 PM
- Punta GordaPGDAllegiant Air · DailyUntil Jan 29, 20277:30a6:27pFirst departure 7:30 AM, last 6:27 PM
- Santa AnaSNAAllegiant Air · 6 a week7:30a2:50pFirst departure 7:30 AM, last 2:50 PM
- SarasotaSRQAllegiant Air · 4 a week8:00a5:53pFirst departure 8:00 AM, last 5:53 PM
- TampaPIEAllegiant Air · 5 a weekUntil Jan 29, 202710:01a3:15pFirst departure 10:01 AM, last 3:15 PM
- WashingtonDCAAmerican Airlines · 2 a day6:00a2:28pFirst departure 6:00 AM, last 2:28 PM
- Los AngelesLAX
Airlines at Des Moines
6
See everywhere you can fly from Des Moines on the dates you're free.
Schedules as of Oct 9, 2026.