Nonstop flights from Des Moines to Houston
United Airlines flies this route twice a day.
DSMDes Moines International
803 mi · 14 flights a week
IAHHouston George Bush Intercontinental
When they leave
Des Moines time6:15a3:02pFirst departure 6:15 AM, last 3:02 PM
One morning flight at 6:15 AM, then one afternoon flight at 3:02 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Des Moines to Houston
United Airlines is the only airline flying nonstop from Des Moines to Houston, twice a day on the Embraer 175.
The first arrival in Houston is at 8:50 AM and the last at 5:25 PM. The flight covers 803 miles.
Flying back, Houston to Des Moines has 14 nonstop flights a week.
Return flights
More from Des Moines
Find the cheapest day to fly from Des Moines to Houston.
Schedules as of Oct 9, 2026.