Nonstop flights from Knoxville
TYS · Knoxville McGhee Tyson
7 airlines fly nonstop from Knoxville to 36 destinations in the United States. The busiest routes are to Atlanta, Chicago (ORD) and Charlotte. 3 routes start or resume in the coming months.
Starting soon
- OrlandoFirst flight · Allegiant AirFirst flight Oct 16, 2026
- BirminghamFirst flight · LabcorpFirst flight Oct 18, 2026
- TampaFirst flight · Southwest AirlinesFirst flight Nov 21, 2026
Ending soon
- FayettevilleLast flight · Delta Air LinesLast flight Oct 9, 2026
- MemphisLast flight · Allegiant AirLast flight Nov 22, 2026
- ChicagoLast flight · Allegiant AirLast flight Nov 29, 2026
Nonstop flights from Knoxville within the United States
36- AtlantaATL
Delta Air Lines · 6 to 9 a day5:40a7:41pFirst departure 5:40 AM, last 7:41 PM - AustinAUS
4 airlines · 8 a week8:30a6:45pFirst departure 8:30 AM, last 6:45 PM - BaltimoreBWISouthwest Airlines · Daily8:05a8:25aFirst departure 8:05 AM, last 8:25 AM
- BirminghamBHM
LabcorpFrom Oct 18 - BostonBOSAllegiant Air · Daily7:00a9:30aFirst departure 7:00 AM, last 9:30 AM
- CharlotteCLTAmerican Airlines · 7 to 8 a day5:15a7:25pFirst departure 5:15 AM, last 7:25 PM
- ChicagoMDWMidwayAllegiant Air · 4 a weekUntil Nov 2911:34a1:58pFirst departure 11:34 AM, last 1:58 PM
- ChicagoORDO'Hare
2 airlines · 8 a day7:00a6:52pFirst departure 7:00 AM, last 6:52 PM - DallasDALLove FieldSouthwest Airlines · Daily1:55p3:35pFirst departure 1:55 PM, last 3:35 PM
- DallasDFWFort WorthAmerican Airlines · 5 to 6 a day6:03a6:50pFirst departure 6:03 AM, last 6:50 PM
- DenverDEN4 airlines · 3 to 4 a day7:00a4:50pFirst departure 7:00 AM, last 4:50 PM
- DestinVPSAllegiant Air · 1 to 2 a day8:51a8:01pFirst departure 8:51 AM, last 8:01 PM
- DetroitDTWDelta Air Lines · 2 to 3 a day7:15a5:22pFirst departure 7:15 AM, last 5:22 PM
- FayettevilleXNADelta Air Lines · 1 a weekUntil Oct 94:45p4:45pDeparts 4:45 PM
Show 22 more
- Fort LauderdaleFLLAllegiant Air · 1 to 2 a day7:15a9:11pFirst departure 7:15 AM, last 9:11 PM
- HoustonHOUWilliam P. HobbyAllegiant Air · 5 a weekUntil Jan 2, 20271:26p5:54pFirst departure 1:26 PM, last 5:54 PM
- HoustonIAHGeorge Bush IntercontinentalUnited Airlines · 3 a day7:15a3:40pFirst departure 7:15 AM, last 3:40 PM
- JacksonvilleJAXAllegiant Air · 4 a week11:24a1:38pFirst departure 11:24 AM, last 1:38 PM
- Key WestEYWAllegiant Air · 5 a weekUntil Mar 5, 20276:00a11:38aFirst departure 6:00 AM, last 11:38 AM
- Las VegasLASAllegiant Air · 6 a week8:20a9:55pFirst departure 8:20 AM, last 9:55 PM
- MemphisMEMAllegiant Air · 2 a weekUntil Nov 224:48p5:38pFirst departure 4:48 PM, last 5:38 PM
- MiamiMIAAmerican Airlines · 10 a week6:06a7:40pFirst departure 6:06 AM, last 7:40 PM
- MinneapolisMSPDelta Air Lines · 1 to 2 a day6:35a6:25pFirst departure 6:35 AM, last 6:25 PM
- NashvilleBNASouthwest Airlines · 2 a day7:10a5:45pFirst departure 7:10 AM, last 5:45 PM
- New YorkLGADelta Air Lines · 2 to 3 a day6:00a5:15pFirst departure 6:00 AM, last 5:15 PM
- NewarkEWR2 airlines · 1 to 3 a day7:10a4:16pFirst departure 7:10 AM, last 4:16 PM
- OrlandoMCOOrlando2 airlines · 1 to 2 a day12:30p6:29pFirst departure 12:30 PM, last 6:29 PM
- OrlandoSFBSanfordAllegiant Air · 2 a weekFrom Oct 169:00a6:27pFirst departure 9:00 AM, last 6:27 PM
- PhiladelphiaPHL2 airlines · 19 a week6:57a6:32pFirst departure 6:57 AM, last 6:32 PM
- PhoenixPHXAllegiant Air · 6 a week6:30a2:53pFirst departure 6:30 AM, last 2:53 PM
- Punta GordaPGDAllegiant Air · Daily8:00a9:41pFirst departure 8:00 AM, last 9:41 PM
- SarasotaSRQAllegiant Air · 5 a weekUntil Mar 1, 20278:10a9:44pFirst departure 8:10 AM, last 9:44 PM
- TampaPIESt. Pete-ClearwaterAllegiant Air · 1 to 2 a day8:00a7:15pFirst departure 8:00 AM, last 7:15 PM
- TampaTPATampaSouthwest Airlines · 1 a weekFrom Nov 213:10p3:10pDeparts 3:10 PM
- WashingtonDCARonald Reagan Washington NationalAmerican Airlines · 2 to 3 a day7:04a7:31pFirst departure 7:04 AM, last 7:31 PM
- WashingtonIADDullesUnited Airlines · 3 to 4 a day5:45a7:20pFirst departure 5:45 AM, last 7:20 PM
- Fort LauderdaleFLL
Airlines at Knoxville
7
See everywhere you can fly from Knoxville on the dates you're free.
Schedules as of Oct 9, 2026.