Nonstop flights from Knoxville to Houston
2 airlines fly from Knoxville (TYS) to 2 Houston airports (IAH and HOU), with up to 4 flights a day.
Routes
2 airport pairs- TYS to IAHMcGhee Tyson to George Bush Intercontinental3 a day
- TYS to HOUMcGhee Tyson to William P. Hobby5 a week
When they leave
Knoxville timeOne morning flight at 7:15 AM, then four in the afternoon, 1:26 PM to 3:40 PM, then two in the evening, 5:39 PM to 5:54 PM.
Every flight
Earliest first
Schedules last checked Sep 21, 2026. Times are local.
Flying from Knoxville to Houston
United Airlines flies most often, 3 times a day on the Embraer 175. Allegiant Air flies 5 times a week on the Airbus A320.
There are 3 or 4 flights every day of the week. The first arrival in Houston is at 8:44 AM and the last at 7:13 PM.
TYS to IAH is the busiest airport pair, with 21 flights a week, then TYS to HOU with 5.
On TYS to HOU, Allegiant Air flies it until Nov 29 and is back on Dec 19.
Flying back, Houston to Knoxville has 24 nonstop flights a week.
Return flights
Find the cheapest day to fly from Knoxville to Houston.
Schedules as of Oct 9, 2026.