Nonstop flights from Knoxville to Charlotte
American Airlines flies this route 7 to 8 times a day.
TYSKnoxville McGhee Tyson
176 mi · 55 flights a week
CLTCharlotte Douglas International
When they leave
Knoxville time5:15a7:25pFirst departure 5:15 AM, last 7:25 PM
Four in the morning, 5:15 AM to 10:08 AM, then three in the afternoon, 12:09 PM to 4:22 PM, then two in the evening, 6:05 PM to 7:25 PM.
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Schedules last checked Sep 22, 2026. Times are local.
Flying from Knoxville to Charlotte
American Airlines is the only airline flying nonstop from Knoxville to Charlotte, 7 to 8 times a day on the Embraer ERJ-145, CRJ 900 and CRJ 700.
There are 7 or 8 flights every day of the week. The first arrival in Charlotte is at 6:42 AM and the last at 8:52 PM. The flight covers 176 miles.
Flying back, Charlotte to Knoxville has 55 nonstop flights a week.
Return flights
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Schedules as of Oct 9, 2026.