Nonstop flights from Fort Myers to St. Louis

Southwest Airlines flies this route 2 to 3 times a day.

RSWFort Myers Southwest Florida International

979 mi · 15 flights a week

STLSt. Louis Lambert International

RSWSTL

When they leave

Fort Myers time

6:10a6:25pFirst departure 6:10 AM, last 6:25 PM

Two in the morning, 6:10 AM to 11:50 AM, then one afternoon flight at 12:40 PM, then two in the evening, 6:15 PM to 6:25 PM.

Every flight

Earliest first

6:10 AM→7:40 AMSouthwest AirlinesBoeing 737 MAX 8Mon, Tue, Wed, Thu, Fri, Sun
11:50 AM→1:20 PMSouthwest AirlinesBoeing 737Sat
12:40 PM→2:10 PMSouthwest AirlinesBoeing 737 MAX 8Sun
6:15 PM→7:50 PMSouthwest AirlinesBoeing 737Tue, Wed, Sun
6:25 PM→8:00 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Thu, Fri, Sat

Schedules last checked Sep 21, 2026. Times are local.

Flying from Fort Myers to St. Louis

Southwest Airlines is the only airline flying nonstop from Fort Myers to St. Louis, 2 to 3 times a day on the Boeing 737 MAX 8 and Boeing 737.

Flights run every day of the week, 3 on Sundays and 2 on the other days. The first arrival in St. Louis is at 7:40 AM and the last at 8:00 PM. The flight covers 979 miles.

Flying back, St. Louis to Fort Myers has 16 nonstop flights a week.

Return flights

St. Louis to Fort MyersView

Find the cheapest day to fly from Fort Myers to St. Louis.

Schedules as of Oct 9, 2026.