Nonstop flights from St. Louis to Fort Myers

Southwest Airlines flies this route 2 to 3 times a day.

STLSt. Louis Lambert International

979 mi · 16 flights a week

RSWFort Myers Southwest Florida International

STLRSW

When they leave

St. Louis time

5:55a8:25pFirst departure 5:55 AM, last 8:25 PM

Four in the morning, 5:55 AM to 10:20 AM, then one afternoon flight at 3:55 PM, then two in the evening, 6:40 PM to 8:25 PM.

Every flight

Earliest first

5:55 AM→9:20 AMSouthwest AirlinesBoeing 737 MAX 8Thu
10:05 AM→1:35 PMSouthwest AirlinesBoeing 737 MAX 8Sun
10:15 AM→1:45 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Tue, Wed, Fri, Sat
10:20 AM→1:45 PMSouthwest AirlinesBoeing 737Thu
3:55 PM→7:25 PMSouthwest AirlinesBoeing 737-700Sun
6:40 PM→10:15 PMSouthwest AirlinesBoeing 737Mon, Tue, Wed, Fri, Sat, Sun
8:25 PM→11:50 PMSouthwest AirlinesBoeing 737-700Thu

Schedules last checked Sep 20, 2026. Times are local.

Flying from St. Louis to Fort Myers

Southwest Airlines is the only airline flying nonstop from St. Louis to Fort Myers, 2 to 3 times a day on the Boeing 737 MAX 8, Boeing 737 and Boeing 737-700.

Flights run every day of the week, 3 on Thursdays and Sundays and 2 on the other days. The first arrival in Fort Myers is at 9:20 AM and the last at 11:50 PM. The flight covers 979 miles.

Flying back, Fort Myers to St. Louis has 15 nonstop flights a week.

Return flights

Fort Myers to St. LouisView

Find the cheapest day to fly from St. Louis to Fort Myers.

Schedules as of Oct 9, 2026.