Nonstop flights from Fort Myers to Charlotte
American Airlines flies this route 3 to 4 times a day.
RSWFort Myers Southwest Florida International
601 mi · 27 flights a week
CLTCharlotte Douglas International
When they leave
Fort Myers time6:22a7:41pFirst departure 6:22 AM, last 7:41 PM
Four in the morning, 6:22 AM to 11:04 AM, then two in the afternoon, 3:02 PM to 3:59 PM, then two in the evening, 6:34 PM to 7:41 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Fort Myers to Charlotte
American Airlines is the only airline flying nonstop from Fort Myers to Charlotte, 3 to 4 times a day on the Boeing 737 and Airbus A321.
There are 3 or 4 flights every day of the week. The first arrival in Charlotte is at 8:20 AM and the last at 9:45 PM. The flight covers 601 miles.
Flying back, Charlotte to Fort Myers has 26 nonstop flights a week.
Return flights
More from Fort Myers
Find the cheapest day to fly from Fort Myers to Charlotte.
Schedules as of Oct 9, 2026.