Nonstop flights from Chicago to St. Louis

2 airlines fly this route, with up to 15 flights a day.

ORDChicago O'Hare International

258 mi · 102 flights a week

STLSt. Louis Lambert International

ORDSTL

When they leave

Chicago time

7:00a11:00pFirst departure 7:00 AM, last 11:00 PM

Five in the morning, 7:00 AM to 11:29 AM, then four in the afternoon, 1:30 PM to 3:35 PM, then six in the evening, 5:45 PM to 11:00 PM.

Every flight

Earliest first

7:00 AM→8:24 AMAmerican AirlinesEmbraer 170Daily
7:05 AM→8:39 AMUnited AirlinesEmbraer 175Mon, Wed, Thu, Fri, Sun
8:40 AM→10:12 AMUnited AirlinesCRJ 700Daily
10:29 AM→12:02 PMUnited AirlinesBoeing 737Daily
11:29 AM→12:54 PMAmerican AirlinesCRJ 700Daily
1:30 PM→2:57 PMUnited AirlinesCRJ 700Mon, Tue, Wed, Thu, Fri, Sun
1:30 PM→2:57 PMUnited AirlinesCRJ 700Sat
2:07 PM→3:38 PMUnited AirlinesBoeing 737Daily
3:00 PM→4:24 PMAmerican AirlinesEmbraer 175Daily
3:35 PM→5:06 PMUnited AirlinesCRJ 700Daily
5:45 PM→7:16 PMUnited AirlinesCRJ 700Daily
5:59 PM→7:27 PMAmerican AirlinesEmbraer 170Daily
7:45 PM→9:17 PMUnited AirlinesCRJ 700Daily
8:29 PM→10:00 PMUnited AirlinesAirbus A319Daily
9:30 PM→10:59 PMUnited AirlinesCRJ 700Mon, Wed, Thu, Fri, Sat, Sun
11:00 PM→12:14 AM⁺¹American AirlinesAirbus A319Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Chicago to St. Louis

United Airlines flies most often, 8 to 10 times a day on the CRJ 700, Boeing 737, Airbus A319 and Embraer 175. American Airlines flies 5 times a day on the Embraer 170, Airbus A319, CRJ 700 and Embraer 175.

Flights run every day of the week, from 13 on Tuesdays to 15 on Mondays, Wednesdays, Thursdays, Fridays and Sundays. The first arrival in St. Louis is at 8:24 AM and the last at 12:14 AM the next day. The flight covers 258 miles.

Flying back, St. Louis to Chicago has 102 nonstop flights a week. Midway (MDW) also has nonstop flights to St. Louis, 33 a week.