Nonstop flights from Chicago to St. Louis
3 airlines fly from 2 Chicago airports (ORD and MDW) to St. Louis (STL), with up to 20 flights a day.
Routes
2 airport pairs- ORD to STLChicago O'Hare to St. Louis Lambert13 to 15 a day
- MDW to STLChicago Midway to St. Louis Lambert3 to 5 a day
When they leave
Chicago timeNine in the morning, 7:00 AM to 11:29 AM, then seven in the afternoon, 1:30 PM to 4:40 PM, then nine in the evening, 5:45 PM to 11:00 PM.
Every flight
Earliest firstSchedules last checked Sep 20, 2026. Times are local.
Flying from Chicago to St. Louis
United Airlines flies most often, 8 to 10 times a day on the CRJ 700, Boeing 737, Airbus A319 and Embraer 175. American Airlines flies 5 times a day on the Embraer 170, Airbus A319, CRJ 700 and Embraer 175. Southwest Airlines flies 3 to 5 times a day on the Boeing 737-700, Boeing 737 MAX 8 and Boeing 737.
Flights run every day of the week, from 17 on Saturdays to 20 on Mondays, Wednesdays, Thursdays, Fridays and Sundays. The first arrival in St. Louis is at 8:24 AM and the last at 12:14 AM the next day.
ORD to STL is the busiest airport pair, with 102 flights a week, then MDW to STL with 33.
Flying back, St. Louis to Chicago has 135 nonstop flights a week.
Return flights
Schedules as of Oct 9, 2026.