Nonstop flights from Phoenix to St. Louis

2 airlines fly this route, with up to 6 flights a day.

PHXPhoenix Sky Harbor International

1,259 mi · 38 flights a week

STLSt. Louis Lambert International

PHXSTL

When they leave

Phoenix time

5:00a6:55pFirst departure 5:00 AM, last 6:55 PM

Three in the morning, 5:00 AM to 7:25 AM, then five in the afternoon, 12:30 PM to 3:28 PM, then two in the evening, 5:40 PM to 6:55 PM.

Every flight

Earliest first

5:00 AM→9:50 AMSouthwest AirlinesBoeing 737 MAX 8Daily
6:00 AM→10:55 AMSouthwest AirlinesBoeing 737 MAX 8Tue, Wed, Sat, Sun
7:25 AM→12:20 PMSouthwest AirlinesBoeing 737-700Mon, Thu, Fri, Sun
12:30 PM→5:37 PMAmerican AirlinesBoeing 737Daily
1:15 PM→6:10 PMSouthwest AirlinesBoeing 737-700Sun
1:20 PM→6:15 PMSouthwest AirlinesBoeing 737Tue, Wed, Sat
1:30 PM→6:20 PMSouthwest AirlinesBoeing 737Mon, Tue, Wed, Thu, Fri
3:28 PM→8:36 PMAmerican AirlinesBoeing 737-800Sun
5:40 PM→10:35 PMSouthwest AirlinesBoeing 737Tue, Wed, Sat
6:55 PM→11:50 PMSouthwest AirlinesBoeing 737Mon, Thu, Fri

Schedules last checked Sep 21, 2026. Times are local.

Flying from Phoenix to St. Louis

Southwest Airlines flies most often, 4 to 5 times a day on the Boeing 737, Boeing 737 MAX 8 and Boeing 737-700. American Airlines flies 1 to 2 times a day on the Boeing 737 and Boeing 737-800.

Flights run every day of the week, 6 on Tuesdays, Wednesdays and Sundays and 5 on the other days. The first arrival in St. Louis is at 9:50 AM and the last at 11:50 PM. The flight covers 1,259 miles.

Flying back, St. Louis to Phoenix has 35 nonstop flights a week.

Return flights

St. Louis to PhoenixView

Find the cheapest day to fly from Phoenix to St. Louis.

Schedules as of Oct 9, 2026.