Nonstop flights from Phoenix to Des Moines
American Airlines flies this route twice a day.
PHXPhoenix Sky Harbor International
1,148 mi · 14 flights a week
DSMDes Moines International
When they leave
Phoenix time8:34a3:57pFirst departure 8:34 AM, last 3:57 PM
One morning flight at 8:34 AM, then one afternoon flight at 3:57 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Phoenix to Des Moines
American Airlines is the only airline flying nonstop from Phoenix to Des Moines, twice a day on the Airbus A319.
The first arrival in Des Moines is at 1:29 PM and the last at 8:46 PM. The flight covers 1,148 miles.
Flying back, Des Moines to Phoenix has 21 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Phoenix to Des Moines.
Schedules as of Oct 9, 2026.