Nonstop flights from Panama City to Santiago

Copa Airlines flies this route 5 to 6 times a day.

PTYPanama City Tocumen International Airport Panama

2,988 mi · 39 flights a week

SCLSantiago Arturo Merino Benitez International

PTYSCL

When they leave

Panama City time

12:01p9:39pFirst departure 12:01 PM, last 9:39 PM

Three in the afternoon, 12:01 PM to 3:51 PM, then three in the evening, 6:15 PM to 9:39 PM.

Every flight

Earliest first

12:01 PM→7:36 PMCopa AirlinesBoeing 737Daily
3:08 PM→10:43 PMCopa AirlinesBoeing 737 MAX 8Daily
3:51 PM→11:26 PMCopa AirlinesBoeing 737 MAX 8Daily
6:15 PM→1:50 AM⁺¹Copa AirlinesBoeing 737 MAX 8Mon, Wed, Thu, Fri
7:25 PM→3:00 AM⁺¹Copa AirlinesBoeing 737 MAX 8Daily
9:39 PM→5:14 AM⁺¹Copa AirlinesBoeing 737 MAX 9Daily

Schedules last checked Sep 21, 2026. Times are local.

Flying from Panama City to Santiago

Copa Airlines is the only airline flying nonstop from Panama City to Santiago, 5 to 6 times a day on the Boeing 737 MAX 8, Boeing 737 and Boeing 737 MAX 9.

There are 5 or 6 flights every day of the week. The first arrival in Santiago is at 7:36 PM and the last at 5:14 AM the next day. The flight covers 2,988 miles.

Flying back, Santiago to Panama City has 39 nonstop flights a week.

Return flights

Santiago to Panama CityView

Find the cheapest day to fly from Panama City to Santiago.

Schedules as of Oct 9, 2026.