Nonstop flights from Panama City to Medellín

Copa Airlines flies this route 7 to 9 times a day.

PTYPanama City Tocumen International Airport Panama

337 mi · 54 flights a week

MDEMedellín Jose Maria Cordova International

PTYMDE

When they leave

Panama City time

6:49a9:24pFirst departure 6:49 AM, last 9:24 PM

Four in the morning, 6:49 AM to 9:29 AM, then three in the afternoon, 12:49 PM to 3:29 PM, then three in the evening, 6:29 PM to 9:24 PM.

Every flight

Earliest first

6:49 AM→8:15 AMCopa AirlinesBoeing 737 MAX 9Daily
8:14 AM→9:40 AMCopa AirlinesBoeing 737 MAX 9Mon, Tue, Wed, Sat
8:16 AM→9:40 AMCopa AirlinesBoeing 737 MAX 9Thu
9:29 AM→10:55 AMCopa AirlinesBoeing 737-800Daily
12:49 PM→2:15 PMCopa AirlinesBoeing 737-800Daily
1:19 PM→2:45 PMCopa AirlinesBoeing 737-800Mon, Tue, Wed, Sat
3:29 PM→4:55 PMCopa AirlinesBoeing 737-800Daily
6:29 PM→7:55 PMCopa AirlinesBoeing 737-800Daily
7:09 PM→8:35 PMCopa AirlinesBoeing 737-800Wed, Fri, Sun
9:24 PM→10:50 PMCopa AirlinesBoeing 737Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Panama City to Medellín

Copa Airlines is the only airline flying nonstop from Panama City to Medellín, 7 to 9 times a day on the Boeing 737-800, Boeing 737 MAX 9 and Boeing 737.

Flights run every day of the week, from 7 on Thursdays, Fridays and Sundays to 9 on Wednesdays. The first arrival in Medellín is at 8:15 AM and the last at 10:50 PM. The flight covers 337 miles.

Flying back, Medellín to Panama City has 54 nonstop flights a week.

Return flights

Medellín to Panama CityView

Find the cheapest day to fly from Panama City to Medellín.

Schedules as of Oct 9, 2026.