Nonstop flights from Panama City to São Paulo

Copa Airlines flies this route 5 to 6 times a day.

PTYPanama City Tocumen International Airport Panama

3,160 mi · 39 flights a week

GRUSão Paulo/Guarulhos-Governor André Franco Montoro International

PTYGRU

When they leave

Panama City time

12:01p9:41pFirst departure 12:01 PM, last 9:41 PM

Three in the afternoon, 12:01 PM to 3:41 PM, then three in the evening, 6:46 PM to 9:41 PM.

Every flight

Earliest first

12:01 PM→8:50 PMCopa AirlinesBoeing 737Daily
3:21 PM→12:10 AM⁺¹Copa AirlinesBoeing 737 MAX 9Daily
3:41 PM→12:30 AM⁺¹Copa AirlinesBoeing 737 MAX 9Daily
6:46 PM→3:35 AM⁺¹Copa AirlinesBoeing 737 MAX 9Tue, Wed, Thu, Sat
7:01 PM→3:50 AM⁺¹Copa AirlinesBoeing 737 MAX 9Daily
9:41 PM→6:30 AM⁺¹Copa AirlinesBoeing 737 MAX 9Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Panama City to São Paulo

Copa Airlines is the only airline flying nonstop from Panama City to São Paulo, 5 to 6 times a day on the Boeing 737 MAX 9 and Boeing 737.

There are 5 or 6 flights every day of the week. The first arrival in São Paulo is at 8:50 PM and the last at 6:30 AM the next day. The flight covers 3,160 miles.

Flying back, São Paulo to Panama City has 39 nonstop flights a week.

Return flights

São Paulo to Panama CityView

Find the cheapest day to fly from Panama City to São Paulo.

Schedules as of Oct 9, 2026.