Nonstop flights from São Paulo to Santiago

2 airlines fly this route.

GRUSão Paulo/Guarulhos-Governor André Franco Montoro International

1,625 mi · 62 flights a week

SCLSantiago Arturo Merino Benitez International

GRUSCL

When they leave

São Paulo time

5:05a11:30pFirst departure 5:05 AM, last 11:30 PM

Four in the morning, 5:05 AM to 9:35 AM, then three in the afternoon, 12:05 PM to 2:55 PM, then five in the evening, 5:50 PM to 11:30 PM.

Every flight

Earliest first

5:05 AM→9:30 AMTurkish AirlinesAirbus A350Mon, Tue, Wed, Thu, Sat, Sun
7:10 AM→11:30 AMLATAM Airlines ChileBoeing 787Mon, Tue, Wed, Thu, Sat, Sun
8:00 AM→12:20 PMLATAM Airlines ChileAirbus A320Mon, Tue, Wed, Sun
9:35 AM→1:55 PMLATAM Airlines ChileBoeing 787Thu, Sat
12:05 PM→4:25 PMLATAM Airlines ChileAirbus A321Mon, Tue, Wed, Thu, Sat, Sun
2:10 PM→6:30 PMLATAM Airlines ChileAirbus A320Mon, Tue, Wed, Thu, Sat, Sun
2:55 PM→7:15 PMLATAM Airlines ChileAirbus A321Mon, Tue, Wed, Thu, Sat, Sun
5:50 PM→10:10 PMLATAM Airlines ChileAirbus A321Mon, Tue, Wed, Thu, Sat, Sun
7:00 PM→11:20 PMLATAM Airlines ChileAirbus A321Mon, Wed, Sat, Sun
8:10 PM→12:40 AM⁺¹LATAM Airlines ChileAirbus A321Mon, Tue, Wed, Thu, Sat, Sun
9:40 PM→2:00 AM⁺¹LATAM Airlines ChileAirbus A320Mon, Tue, Wed, Thu, Sat, Sun
11:30 PM→3:50 AM⁺¹LATAM Airlines ChileAirbus A320Mon, Wed, Sat, Sun

Schedules last checked Oct 9, 2026. Times are local.

Flying from São Paulo to Santiago

LATAM Airlines Chile flies most often, 56 times a week on the Airbus A321, Airbus A320 and Boeing 787. Turkish Airlines flies 6 times a week on the Airbus A350.

Flights run every day except Fridays, up to 11 a day. The first arrival in Santiago is at 9:30 AM and the last at 3:50 AM the next day. The flight covers 1,625 miles.

Flying back, Santiago to São Paulo has 96 nonstop flights a week.

Return flights

Santiago to São PauloView

Find the cheapest day to fly from São Paulo to Santiago.

Schedules as of Oct 9, 2026.