Nonstop flights from La Serena to Santiago

3 airlines fly this route, with up to 9 flights a day.

LSCLa Serena La Florida

242 mi · 50 flights a week

SCLSantiago Arturo Merino Benitez International

LSCSCL

When they leave

La Serena time

7:51a10:44pFirst departure 7:51 AM, last 10:44 PM

Eight in the morning, 7:51 AM to 11:16 AM, then five in the afternoon, 1:29 PM to 4:44 PM, then seven in the evening, 5:02 PM to 10:44 PM.

Every flight

Earliest first

7:51 AM→8:51 AMLATAM Airlines ChileAirbus A320Daily
7:57 AM→8:57 AMLATAM Airlines ChileAirbus A321Daily
9:40 AM→10:40 AMLATAM Airlines ChileAirbus A320Mon, Tue, Wed, Thu, Sun
10:51 AM→11:51 AMJetSMARTAirbus A320Sat
10:59 AM→12:00 PMSKY AirlineAirbus A320neoThu
11:01 AM→12:02 PMSKY AirlineAirbus A320neoThu, Sun
11:04 AM→12:05 PMSKY AirlineAirbus A320neoTue
11:16 AM→12:16 PMLATAM Airlines ChileAirbus A320Mon, Wed
1:29 PM→2:30 PMSKY AirlineAirbus A321neoSat
3:42 PM→4:43 PMSKY AirlineAirbus A320neoThu
3:53 PM→4:51 PMLATAM Airlines ChileAirbus A320Thu, Fri, Sun
4:24 PM→5:25 PMSKY AirlineAirbus A320neoThu, Fri
4:44 PM→5:45 PMSKY AirlineAirbus A320neoFri
5:02 PM→6:03 PMSKY AirlineAirbus A320neoTue
5:29 PM→6:30 PMSKY AirlineAirbus A321neoWed
5:47 PM→6:48 PMSKY AirlineAirbus A320neoMon
5:57 PM→6:58 PMSKY AirlineAirbus A320neoWed, Fri
6:50 PM→7:51 PMSKY AirlineAirbus A320neoWed
10:32 PM→11:30 PMLATAM Airlines ChileAirbus A320Wed, Fri, Sun
10:32 PM→11:30 PMLATAM Airlines ChileAirbus A320Fri
10:32 PM→11:30 PMLATAM Airlines ChileAirbus A320Mon, Tue, Thu, Sat
10:44 PM→11:44 PMJetSMARTAirbus A320Wed, Fri

Schedules last checked Sep 19, 2026. Times are local.

Flying from La Serena to Santiago

LATAM Airlines Chile flies most often, 3 to 5 times a day on the Airbus A320 and Airbus A321. SKY Airline flies 1 to 4 times a day on the Airbus A320neo and Airbus A321neo. JetSMART flies on Wednesdays, Fridays and Saturdays with the Airbus A320.

Flights run every day of the week, from 5 on Saturdays to 9 on Wednesdays, Thursdays and Fridays. The first arrival in Santiago is at 8:51 AM and the last at 11:44 PM. The flight covers 242 miles.

Flying back, Santiago to La Serena has 48 nonstop flights a week.

Return flights

Santiago to La SerenaView

More to Santiago

Find the cheapest day to fly from La Serena to Santiago.

Schedules as of Oct 9, 2026.