Nonstop flights from Tampa to St. Louis

Southwest Airlines flies this route 3 to 4 times a day.

TPATampa International

869 mi · 22 flights a week

STLSt. Louis Lambert International

TPASTL

When they leave

Tampa time

6:20a8:55pFirst departure 6:20 AM, last 8:55 PM

Three in the morning, 6:20 AM to 10:35 AM, then two in the afternoon, 12:35 PM to 3:25 PM, then two in the evening, 6:30 PM to 8:55 PM.

Every flight

Earliest first

6:20 AM→7:40 AMSouthwest AirlinesBoeing 737 MAX 8Mon, Thu, Fri, Sun
6:25 AM→7:45 AMSouthwest AirlinesBoeing 737 MAX 8Tue, Wed, Sat, Sun
10:35 AM→12:00 PMSouthwest AirlinesBoeing 737-700Mon, Thu, Fri, Sat
12:35 PM→2:00 PMSouthwest AirlinesBoeing 737 MAX 8Sat
3:25 PM→4:50 PMSouthwest AirlinesBoeing 737 MAX 8Tue, Wed
6:30 PM→7:55 PMSouthwest AirlinesBoeing 737 MAX 8Tue, Wed, Sun
8:55 PM→10:20 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Thu, Fri, Sun

Schedules last checked Sep 22, 2026. Times are local.

Flying from Tampa to St. Louis

Southwest Airlines is the only airline flying nonstop from Tampa to St. Louis, 3 to 4 times a day on the Boeing 737 MAX 8 and Boeing 737-700.

Flights run every day of the week, 4 on Sundays and 3 on the other days. The first arrival in St. Louis is at 7:40 AM and the last at 10:20 PM. The flight covers 869 miles.

Flying back, St. Louis to Tampa has 22 nonstop flights a week.

Return flights

St. Louis to TampaView

Find the cheapest day to fly from Tampa to St. Louis.

Schedules as of Oct 9, 2026.