Nonstop flights from Panama City to San Francisco
Copa Airlines flies this route 1 to 2 times a day.
PTYPanama City Tocumen International Airport Panama
3,321 mi · 10 flights a week
SFOSan Francisco International
When they leave
Panama City time12:38p6:08pFirst departure 12:38 PM, last 6:08 PM
One afternoon flight at 12:38 PM, then one evening flight at 6:08 PM.
Every flight
Earliest first
Schedules last checked Sep 8, 2026. Times are local.
Flying from Panama City to San Francisco
Copa Airlines is the only airline flying nonstop from Panama City to San Francisco, 1 to 2 times a day on the Boeing 737 MAX 9.
Flights run every day of the week, 2 on Wednesdays, Thursdays and Sundays and 1 on the other days. The first arrival in San Francisco is at 5:59 PM and the last at 11:40 PM. The flight covers 3,321 miles.
Flying back, San Francisco to Panama City has 11 nonstop flights a week.
Return flights
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Schedules as of Oct 9, 2026.