Nonstop flights from Panama City to Guayaquil

Copa Airlines flies this route 6 to 7 times a day until Mar 7, 2027.

PTYPanama City Tocumen International Airport Panama

775 mi · 46 flights a week

GYEGuayaquil José Joaquín de Olmedo International

PTYGYE

When they leave

Panama City time

8:20a9:48pFirst departure 8:20 AM, last 9:48 PM

Three in the morning, 8:20 AM to 11:21 AM, then one afternoon flight at 3:17 PM, then three in the evening, 6:39 PM to 9:48 PM.

Every flight

Earliest first

8:20 AM→10:34 AMCopa AirlinesUntil Mar 7, 2027Boeing 737 MAX 9Mon, Tue, Thu, Sat
9:08 AM→11:22 AMCopa AirlinesUntil Mar 7, 2027Boeing 737 MAX 9Daily
11:21 AM→1:35 PMCopa AirlinesUntil Mar 7, 2027Boeing 737-800Daily
3:17 PM→5:31 PMCopa AirlinesUntil Mar 7, 2027Boeing 737 MAX 9Daily
6:39 PM→8:53 PMCopa AirlinesUntil Mar 7, 2027Boeing 737 MAX 9Daily
9:24 PM→11:38 PMCopa AirlinesUntil Mar 7, 2027Boeing 737-800Daily
9:48 PM→12:02 AM⁺¹Copa AirlinesUntil Mar 7, 2027Boeing 737-800Daily

Schedules last checked Sep 20, 2026. Times are local.

Flying from Panama City to Guayaquil

Copa Airlines is the only airline flying nonstop from Panama City to Guayaquil, 6 to 7 times a day on the Boeing 737 MAX 9 and Boeing 737-800.

There are 6 or 7 flights every day of the week. The first arrival in Guayaquil is at 10:34 AM and the last at 12:02 AM the next day. The flight covers 775 miles.

Flying back, Guayaquil to Panama City has 45 nonstop flights a week.

Return flights

Guayaquil to Panama CityView

More to Guayaquil

Find the cheapest day to fly from Panama City to Guayaquil.

Schedules as of Oct 9, 2026.