Nonstop flights from Guayaquil to Panama City

Copa Airlines flies this route 6 to 7 times a day until Feb 24, 2027.

GYEGuayaquil José Joaquín de Olmedo International

775 mi · 45 flights a week

PTYPanama City Tocumen International Airport Panama

GYEPTY

When they leave

Guayaquil time

4:13a6:28pFirst departure 4:13 AM, last 6:28 PM

One overnight flight at 4:13 AM, then three in the morning, 6:00 AM to 11:48 AM, then two in the afternoon, 12:22 PM to 2:37 PM, then one evening flight at 6:28 PM.

Every flight

Earliest first

4:13 AM→6:25 AMCopa AirlinesUntil Feb 24, 2027Boeing 737 MAX 9Daily
6:00 AM→8:12 AMCopa AirlinesUntil Feb 24, 2027Boeing 737Tue, Wed, Thu, Fri, Sat, Sun
8:28 AM→10:40 AMCopa AirlinesUntil Feb 24, 2027Boeing 737Daily
11:48 AM→2:00 PMCopa AirlinesUntil Feb 24, 2027Boeing 737 MAX 9Mon, Tue, Thu, Sat
12:22 PM→2:34 PMCopa AirlinesUntil Feb 24, 2027Boeing 737 MAX 9Daily
2:37 PM→4:49 PMCopa AirlinesUntil Feb 24, 2027Boeing 737Daily
6:28 PM→8:40 PMCopa AirlinesUntil Feb 24, 2027Boeing 737 MAX 9Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Guayaquil to Panama City

Copa Airlines is the only airline flying nonstop from Guayaquil to Panama City, 6 to 7 times a day on the Boeing 737 MAX 9 and Boeing 737.

Flights run every day of the week, 7 on Tuesdays, Thursdays and Saturdays and 6 on the other days. The first arrival in Panama City is at 6:25 AM and the last at 8:40 PM. The flight covers 775 miles.

Flying back, Panama City to Guayaquil has 46 nonstop flights a week.

Return flights

Panama City to GuayaquilView

More to Panama City

Find the cheapest day to fly from Guayaquil to Panama City.

Schedules as of Oct 9, 2026.