Nonstop flights from Philadelphia to St. Louis

2 airlines fly this route, with up to 5 flights a day.

PHLPhiladelphia International

812 mi · 33 flights a week

STLSt. Louis Lambert International

PHLSTL

When they leave

Philadelphia time

6:20a10:01pFirst departure 6:20 AM, last 10:01 PM

Four in the morning, 6:20 AM to 11:55 AM, then two in the afternoon, 2:45 PM to 3:28 PM, then two in the evening, 6:35 PM to 10:01 PM.

Every flight

Earliest first

6:20 AM→7:35 AMSouthwest AirlinesUntil Mar 12, 2027, back Apr 2, 2027Boeing 737-700Mon, Thu, Fri, Sun
6:25 AM→7:40 AMSouthwest AirlinesUntil Mar 12, 2027, back Apr 2, 2027Boeing 737Tue, Wed
9:18 AM→10:52 AMAmerican AirlinesCRJ 900Mon, Tue, Wed, Thu, Fri, Sun
11:55 AM→1:15 PMSouthwest AirlinesUntil Mar 12, 2027, back Apr 2, 2027Boeing 737 MAX 8Sat
2:45 PM→4:05 PMSouthwest AirlinesUntil Mar 12, 2027, back Apr 2, 2027Boeing 737-700Tue, Wed, Sun
3:28 PM→5:01 PMAmerican AirlinesAirbus A319Daily
6:35 PM→8:00 PMSouthwest AirlinesUntil Mar 12, 2027, back Apr 2, 2027Boeing 737Mon, Thu, Fri
10:01 PM→11:34 PMAmerican AirlinesAirbus A319Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Philadelphia to St. Louis

American Airlines flies most often, 2 to 3 times a day on the Airbus A319 and CRJ 900. Southwest Airlines flies 1 to 2 times a day on the Boeing 737, Boeing 737-700 and Boeing 737 MAX 8.

Flights run every day of the week, from 3 on Saturdays to 5 on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays and Sundays. The first arrival in St. Louis is at 7:35 AM and the last at 11:34 PM. The flight covers 812 miles.

Southwest Airlines flies it until Mar 12, 2027 and is back on Apr 2, 2027.

Flying back, St. Louis to Philadelphia has 33 nonstop flights a week.