Nonstop flights from Denver to Knoxville

3 airlines fly this route, with up to 4 flights a day.

DENDenver International

1,160 mi · 23 flights a week

TYSKnoxville McGhee Tyson

DENTYS

When they leave

Denver time

9:11a5:35pFirst departure 9:11 AM, last 5:35 PM

Four in the morning, 9:11 AM to 11:40 AM, then one evening flight at 5:35 PM.

Every flight

Earliest first

9:11 AM→2:01 PMAllegiant AirUntil Nov 28Airbus A320Sun
9:11 AM→2:01 PMAllegiant AirUntil Nov 28Airbus A320Thu
11:00 AM→3:54 PMUnited AirlinesAirbus A320Daily
11:10 AM→3:55 PMSouthwest AirlinesBoeing 737-700Mon, Thu, Fri
11:40 AM→4:30 PMSouthwest AirlinesBoeing 737-700Tue, Wed, Sat, Sun
5:35 PM→10:29 PMUnited AirlinesAirbus A320Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Denver to Knoxville

United Airlines flies most often, twice a day on the Airbus A320. Southwest Airlines flies daily on the Boeing 737-700. Allegiant Air flies on Thursdays and Sundays with the Airbus A320.

Flights run every day of the week, 4 on Thursdays and Sundays and 3 on the other days. The first arrival in Knoxville is at 2:01 PM and the last at 10:29 PM. The flight covers 1,160 miles.

Allegiant Air flies it until Nov 28. Frontier Airlines stopped flying it after Aug 17.

Flying back, Knoxville to Denver has 23 nonstop flights a week.

Return flights

Knoxville to DenverView

Find the cheapest day to fly from Denver to Knoxville.

Schedules as of Oct 9, 2026.