Nonstop flights from St. Louis to Cleveland
Southwest Airlines flies this route twice a day.
STLSt. Louis Lambert International
487 mi · 14 flights a week
CLECleveland Hopkins International
When they leave
St. Louis time10:40a7:40pFirst departure 10:40 AM, last 7:40 PM
One morning flight at 10:40 AM, then one afternoon flight at 4:20 PM, then three in the evening, 6:55 PM to 7:40 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from St. Louis to Cleveland
Southwest Airlines is the only airline flying nonstop from St. Louis to Cleveland, twice a day on the Boeing 737 MAX 8 and Boeing 737-700.
The first arrival in Cleveland is at 1:10 PM and the last at 10:10 PM. The flight covers 487 miles.
Flying back, Cleveland to St. Louis has 14 nonstop flights a week.
Return flights
More from St. Louis
Find the cheapest day to fly from St. Louis to Cleveland.
Schedules as of Oct 9, 2026.