Nonstop flights from Panama City to Chicago
Copa Airlines flies this route 1 to 2 times a day.
PTYPanama City Tocumen International Airport Panama
2,332 mi · 13 flights a week
ORDChicago O'Hare International
When they leave
Panama City time8:10a7:25pFirst departure 8:10 AM, last 7:25 PM
One morning flight at 8:10 AM, then one evening flight at 7:25 PM.
Every flight
Earliest first
Schedules last checked Sep 21, 2026. Times are local.
Flying from Panama City to Chicago
Copa Airlines is the only airline flying nonstop from Panama City to Chicago, 1 to 2 times a day on the Boeing 737 MAX 8 and Boeing 737-800.
There are 1 or 2 flights every day of the week. The first arrival in Chicago is at 1:59 PM and the last at 1:02 AM the next day. The flight covers 2,332 miles.
Flying back, Chicago to Panama City has 13 nonstop flights a week.
Return flights
More from Panama City
Find the cheapest day to fly from Panama City to Chicago.
Schedules as of Oct 9, 2026.