Nonstop flights from Panama City to Cartagena

Copa Airlines flies this route 4 to 5 times a day.

PTYPanama City Tocumen International Airport Panama

280 mi · 31 flights a week

CTGCartagena Rafael Núñez International

PTYCTG

When they leave

Panama City time

6:51a9:46pFirst departure 6:51 AM, last 9:46 PM

Three in the morning, 6:51 AM to 9:46 AM, then two in the afternoon, 12:51 PM to 4:41 PM, then one evening flight at 9:46 PM.

Every flight

Earliest first

6:51 AM→8:05 AMCopa AirlinesBoeing 737 MAX 9Mon, Thu, Sun
7:26 AM→8:40 AMCopa AirlinesBoeing 737Daily
9:46 AM→11:00 AMCopa AirlinesBoeing 737Tue, Wed, Fri, Sat
12:51 PM→2:05 PMCopa AirlinesBoeing 737Daily
4:41 PM→5:55 PMCopa AirlinesBoeing 737 MAX 9Mon, Thu, Sun
9:46 PM→11:00 PMCopa AirlinesBoeing 737Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Panama City to Cartagena

Copa Airlines is the only airline flying nonstop from Panama City to Cartagena, 4 to 5 times a day on the Boeing 737 and Boeing 737 MAX 9.

Flights run every day of the week, 5 on Mondays, Thursdays and Sundays and 4 on the other days. The first arrival in Cartagena is at 8:05 AM and the last at 11:00 PM. The flight covers 280 miles.

Flying back, Cartagena to Panama City has 31 nonstop flights a week.

Return flights

Cartagena to Panama CityView

More to Cartagena

Find the cheapest day to fly from Panama City to Cartagena.

Schedules as of Oct 9, 2026.