Nonstop flights from Panama City to Cali
Copa Airlines flies this route 4 to 5 times a day.
PTYPanama City Tocumen International Airport Panama
434 mi · 33 flights a week
CLOCali Alfonso Bonilla Aragón International
When they leave
Panama City time9:30a9:55pFirst departure 9:30 AM, last 9:55 PM
One morning flight at 9:30 AM, then three in the afternoon, 12:34 PM to 3:55 PM, then one evening flight at 9:55 PM.
Every flight
Earliest first
Schedules last checked Sep 20, 2026. Times are local.
Flying from Panama City to Cali
Copa Airlines is the only airline flying nonstop from Panama City to Cali, 4 to 5 times a day on the Boeing 737-800, Boeing 737 and Boeing 737 MAX 9.
There are 4 or 5 flights every day of the week. The first arrival in Cali is at 11:08 AM and the last at 11:33 PM. The flight covers 434 miles.
Flying back, Cali to Panama City has 33 nonstop flights a week.
Return flights
More from Panama City
More to Cali
Find the cheapest day to fly from Panama City to Cali.
Schedules as of Oct 9, 2026.