Nonstop flights from Chicago to Buffalo

Southwest Airlines flies this route 2 to 3 times a day.

MDWChicago Midway International

467 mi · 20 flights a week

BUFBuffalo Niagara International

MDWBUF

When they leave

Chicago time

8:05a6:20pFirst departure 8:05 AM, last 6:20 PM

One morning flight at 8:05 AM, then three in the afternoon, 12:45 PM to 3:15 PM, then three in the evening, 6:00 PM to 6:20 PM.

Every flight

Earliest first

8:05 AM→10:45 AMSouthwest AirlinesBoeing 737 MAX 8Daily
12:45 PM→3:15 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Tue, Wed, Thu, Fri
1:55 PM→4:25 PMSouthwest AirlinesBoeing 737-700Sun
3:15 PM→5:40 PMSouthwest AirlinesBoeing 737-700Sat
6:00 PM→8:35 PMSouthwest AirlinesBoeing 737Tue, Wed
6:05 PM→8:40 PMSouthwest AirlinesBoeing 737-700Sun
6:20 PM→8:50 PMSouthwest AirlinesBoeing 737-700Mon, Thu, Fri

Schedules last checked Sep 21, 2026. Times are local.

Flying from Chicago to Buffalo

Southwest Airlines is the only airline flying nonstop from Chicago to Buffalo, 2 to 3 times a day on the Boeing 737-700, Boeing 737 MAX 8 and Boeing 737.

There are 2 or 3 flights every day of the week. The first arrival in Buffalo is at 10:45 AM and the last at 8:50 PM. The flight covers 467 miles.

Flying back, Buffalo to Chicago has 20 nonstop flights a week. O'Hare (ORD) also has nonstop flights to Buffalo, 38 a week.

Return flights

Buffalo to ChicagoView

Every Chicago airport

All Chicago to Buffalo flightsView

Find the cheapest day to fly from Chicago to Buffalo.

Schedules as of Oct 9, 2026.