Nonstop flights from Detroit to Buffalo
Delta Air Lines flies this route 4 to 5 times a day.
DTWDetroit Metropolitan Wayne County
240 mi · 34 flights a week
BUFBuffalo Niagara International
When they leave
Detroit time7:00a10:50pFirst departure 7:00 AM, last 10:50 PM
Two in the morning, 7:00 AM to 10:10 AM, then one afternoon flight at 2:00 PM, then two in the evening, 5:50 PM to 10:50 PM.
Every flight
Earliest first
Schedules last checked Sep 21, 2026. Times are local.
Flying from Detroit to Buffalo
Delta Air Lines is the only airline flying nonstop from Detroit to Buffalo, 4 to 5 times a day on the CRJ 900, Airbus A319 and CRJ 700.
There are 4 or 5 flights every day of the week. The first arrival in Buffalo is at 8:15 AM and the last at 11:58 PM. The flight covers 240 miles.
Flying back, Buffalo to Detroit has 34 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Detroit to Buffalo.
Schedules as of Oct 9, 2026.