Nonstop flights from Philadelphia to Buffalo

American Airlines flies this route 4 to 6 times a day.

PHLPhiladelphia International

278 mi · 40 flights a week

BUFBuffalo Niagara International

PHLBUF

When they leave

Philadelphia time

8:43a10:20pFirst departure 8:43 AM, last 10:20 PM

Three in the morning, 8:43 AM to 11:05 AM, then three in the afternoon, 12:50 PM to 3:25 PM, then three in the evening, 5:35 PM to 10:20 PM.

Every flight

Earliest first

8:43 AM→10:16 AMAmerican AirlinesEmbraer ERJ-145Tue
8:45 AM→10:18 AMAmerican AirlinesEmbraer ERJ-145Mon, Wed, Thu, Fri, Sat, Sun
11:05 AM→12:38 PMAmerican AirlinesEmbraer ERJ-145Mon, Wed, Thu, Fri, Sat, Sun
12:50 PM→2:19 PMAmerican AirlinesEmbraer ERJ-145Tue
12:55 PM→2:26 PMAmerican AirlinesEmbraer ERJ-145Mon, Wed, Thu, Fri, Sat, Sun
3:25 PM→4:56 PMAmerican AirlinesEmbraer ERJ-145Mon, Wed, Thu, Fri, Sat, Sun
5:35 PM→7:07 PMAmerican AirlinesEmbraer ERJ-145Mon, Wed, Thu, Fri, Sat, Sun
5:40 PM→7:12 PMAmerican AirlinesEmbraer ERJ-145Tue
10:20 PM→11:56 PMAmerican AirlinesEmbraer ERJ-145Mon, Wed, Thu, Fri, Sat, Sun
10:20 PM→11:53 PMAmerican AirlinesEmbraer ERJ-145Tue

Schedules last checked Sep 19, 2026. Times are local.

Flying from Philadelphia to Buffalo

American Airlines is the only airline flying nonstop from Philadelphia to Buffalo, 4 to 6 times a day on the Embraer ERJ-145.

Flights run every day of the week, from 4 on Tuesdays to 6 on Mondays, Wednesdays, Thursdays, Fridays, Saturdays and Sundays. The first arrival in Buffalo is at 10:16 AM and the last at 11:56 PM. The flight covers 278 miles.

Flying back, Buffalo to Philadelphia has 41 nonstop flights a week.

Return flights

Buffalo to PhiladelphiaView

Find the cheapest day to fly from Philadelphia to Buffalo.

Schedules as of Oct 9, 2026.