Nonstop flights from St. Louis to San Antonio

Southwest Airlines flies this route 1 to 2 times a day.

STLSt. Louis Lambert International

787 mi · 13 flights a week

SATSan Antonio International

STLSAT

When they leave

St. Louis time

8:30a9:15pFirst departure 8:30 AM, last 9:15 PM

Two in the morning, 8:30 AM to 8:40 AM, then one afternoon flight at 2:25 PM, then two in the evening, 8:45 PM to 9:15 PM.

Every flight

Earliest first

8:30 AM→10:35 AMSouthwest AirlinesBoeing 737-700Mon, Thu, Fri
8:40 AM→10:50 AMSouthwest AirlinesBoeing 737Tue, Wed
2:25 PM→4:30 PMSouthwest AirlinesBoeing 737Sat
8:45 PM→10:55 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Tue, Wed, Thu, Fri, Sun
9:15 PM→11:20 PMSouthwest AirlinesBoeing 737-700Sun

Schedules last checked Sep 20, 2026. Times are local.

Flying from St. Louis to San Antonio

Southwest Airlines is the only airline flying nonstop from St. Louis to San Antonio, 1 to 2 times a day on the Boeing 737, Boeing 737-700 and Boeing 737 MAX 8.

There are 1 or 2 flights every day of the week. The first arrival in San Antonio is at 10:35 AM and the last at 11:20 PM. The flight covers 787 miles.

Flying back, San Antonio to St. Louis has 13 nonstop flights a week.

Return flights

San Antonio to St. LouisView

Find the cheapest day to fly from St. Louis to San Antonio.

Schedules as of Oct 9, 2026.