Nonstop flights from St. Louis to Charlotte

2 airlines fly this route, with up to 6 flights a day.

STLSt. Louis Lambert International

574 mi · 33 flights a week

CLTCharlotte Douglas International

STLCLT

When they leave

St. Louis time

5:23a3:25pFirst departure 5:23 AM, last 3:25 PM

Four in the morning, 5:23 AM to 10:22 AM, then four in the afternoon, 12:41 PM to 3:25 PM.

Every flight

Earliest first

5:23 AM→8:17 AMAmerican AirlinesBoeing 737Sun
6:54 AM→9:49 AMAmerican AirlinesBoeing 737Daily
8:34 AM→11:29 AMAmerican AirlinesBoeing 737Daily
10:22 AM→1:15 PMAmerican AirlinesBoeing 737Mon, Tue, Wed, Thu, Fri, Sat
12:41 PM→3:36 PMAmerican AirlinesAirbus A320Sat, Sun
2:45 PM→5:35 PMSouthwest AirlinesBoeing 737 MAX 8Mon, Thu, Fri
3:05 PM→5:55 PMSouthwest AirlinesBoeing 737-700Sun
3:25 PM→6:22 PMAmerican AirlinesBoeing 737Mon, Tue, Wed, Thu, Fri, Sun

Schedules last checked Sep 12, 2026. Times are local.

Flying from St. Louis to Charlotte

American Airlines flies most often, 4 to 5 times a day on the Boeing 737 and Airbus A320. Southwest Airlines flies 4 times a week on the Boeing 737 MAX 8 and Boeing 737-700.

Flights run every day of the week, from 4 on Tuesdays, Wednesdays and Saturdays to 6 on Sundays. The first arrival in Charlotte is at 8:17 AM and the last at 6:22 PM. The flight covers 574 miles.

Flying back, Charlotte to St. Louis has 34 nonstop flights a week.

Return flights

Charlotte to St. LouisView

Find the cheapest day to fly from St. Louis to Charlotte.

Schedules as of Oct 9, 2026.