Nonstop flights from Santiago to Antofagasta

3 airlines fly this route, with up to 22 flights a day.

SCLSantiago Arturo Merino Benitez International

688 mi · 116 flights a week

ANFAntofagasta

SCLANF

When they leave

Santiago time

4:31a10:31pFirst departure 4:31 AM, last 10:31 PM

Three overnight flights, 4:31 AM to 4:58 AM, then 25 in the morning, 5:00 AM to 11:50 AM, then six in the afternoon, 1:12 PM to 4:31 PM, then nine in the evening, 5:23 PM to 10:31 PM.

Every flight

Earliest first

4:31 AM→6:33 AMLATAM Airlines ChileAirbus A320Mon, Tue, Thu, Fri, Sat
4:55 AM→6:57 AMLATAM Airlines ChileAirbus A320Mon, Tue, Sun
4:58 AM→7:00 AMLATAM Airlines ChileAirbus A320Wed, Thu, Fri, Sat, Sun
5:00 AM→7:02 AMSKY AirlineAirbus A321neoMon
5:15 AM→7:17 AMLATAM Airlines ChileAirbus A321Mon, Tue, Wed, Thu, Sat, Sun
5:57 AM→7:59 AMLATAM Airlines ChileAirbus A321Mon, Tue, Wed, Fri, Sun
5:59 AM→8:01 AMLATAM Airlines ChileAirbus A321Mon, Wed, Thu, Fri
6:00 AM→8:02 AMSKY AirlineAirbus A320neoTue, Wed, Thu, Fri
6:02 AM→8:07 AMJetSMARTAirbus A320Tue, Thu, Sat
6:12 AM→8:14 AMLATAM Airlines ChileAirbus A320Daily
6:45 AM→8:47 AMLATAM Airlines ChileAirbus A321Mon, Tue, Thu, Fri, Sun
6:46 AM→8:48 AMLATAM Airlines ChileAirbus A321Wed, Fri, Sun
7:01 AM→9:06 AMJetSMARTAirbus A320Tue, Wed, Fri
7:13 AM→9:18 AMJetSMARTAirbus A320Sun
7:52 AM→9:54 AMLATAM Airlines ChileAirbus A320Mon
7:53 AM→9:55 AMLATAM Airlines ChileAirbus A321Tue, Thu
7:54 AM→9:59 AMJetSMARTAirbus A321Mon
8:37 AM→10:42 AMJetSMARTAirbus A320Wed
8:47 AM→10:49 AMLATAM Airlines ChileAirbus A321Tue, Wed, Fri, Sat, Sun
9:00 AM→11:02 AMSKY AirlineAirbus A321neoMon, Sat
9:46 AM→11:48 AMLATAM Airlines ChileAirbus A321Mon, Wed, Thu, Fri
9:49 AM→11:54 AMJetSMARTAirbus A320Thu
10:16 AM→12:20 PMLATAM Airlines ChileAirbus A321Mon, Tue, Thu
10:36 AM→12:40 PMLATAM Airlines ChileAirbus A321Mon, Wed, Thu, Fri
10:46 AM→12:50 PMLATAM Airlines ChileAirbus A321Mon, Tue, Wed, Thu
10:58 AM→1:00 PMSKY AirlineAirbus A320neoThu
11:30 AM→1:32 PMSKY AirlineAirbus A320neoTue, Sun
11:50 AM→1:52 PMSKY AirlineAirbus A321neoMon
1:12 PM→3:16 PMLATAM Airlines ChileAirbus A321Mon, Wed, Fri
1:17 PM→3:22 PMJetSMARTAirbus A320Mon
3:15 PM→5:17 PMSKY AirlineAirbus A321neoTue, Thu, Fri
3:28 PM→5:32 PMLATAM Airlines ChileAirbus A321Wed, Thu
3:31 PM→5:35 PMLATAM Airlines ChileAirbus A320Tue, Wed, Sun
4:31 PM→6:33 PMSKY AirlineAirbus A321neoThu, Sun
5:23 PM→7:27 PMLATAM Airlines ChileAirbus A320Mon, Tue, Wed, Thu
6:20 PM→8:22 PMSKY AirlineAirbus A320neoFri
6:31 PM→8:33 PMSKY AirlineAirbus A321neoThu
8:30 PM→10:32 PMSKY AirlineAirbus A320neoWed
8:34 PM→10:38 PMLATAM Airlines ChileAirbus A321Tue, Thu
8:47 PM→10:51 PMLATAM Airlines ChileAirbus A320Mon
8:55 PM→10:59 PMLATAM Airlines ChileAirbus A320Tue, Thu
9:11 PM→11:15 PMLATAM Airlines ChileAirbus A321Mon, Tue
10:31 PM→12:35 AM⁺¹LATAM Airlines ChileAirbus A321Mon

Schedules last checked Sep 19, 2026. Times are local.

Flying from Santiago to Antofagasta

LATAM Airlines Chile flies most often, 5 to 17 times a day on the Airbus A321 and Airbus A320. SKY Airline flies 1 to 5 times a day on the Airbus A321neo and Airbus A320neo. JetSMART flies 1 to 2 times a day on the Airbus A320 and Airbus A321.

Flights run every day of the week, from 7 on Saturdays to 22 on Mondays and Thursdays. The first arrival in Antofagasta is at 6:33 AM and the last at 12:35 AM the next day. The flight covers 688 miles.

Flying back, Antofagasta to Santiago has 94 nonstop flights a week.

Return flights

Antofagasta to SantiagoView

More from Santiago

Find the cheapest day to fly from Santiago to Antofagasta.

Schedules as of Oct 9, 2026.