Nonstop flights from Madrid to Brussels

4 airlines fly this route.

MADAdolfo Suárez Madrid-Barajas

818 mi · 52 flights a week · about 2h 25m

BRUBrussels

MADBRU

When they leave

Madrid time

6:25a8:55pFirst departure 6:25 AM, last 8:55 PM

Three in the morning, 6:25 AM to 9:05 AM, then five in the afternoon, 12:20 PM to 4:35 PM, then three in the evening, 5:30 PM to 8:55 PM.

Every flight

Earliest first

6:25 AM→8:50 AMBrussels AirlinesAirbus A320neo · 2h 25mMon, Tue, Wed, Thu, Fri
7:20 AM→9:50 AMAir EuropaBoeing 737 MAX 8 · 2h 30mMon, Tue, Wed, Thu, Fri, Sun
9:05 AM→11:30 AMIberiaAirbus A320 · 2h 25mMon, Tue, Wed, Thu, Fri, Sun
12:20 PM→2:45 PMIberiaCRJ 1000 · 2h 25mMon, Fri
12:35 PM→2:50 PMBrussels AirlinesAirbus A320 · 2h 15mMon, Tue, Wed, Thu, Fri
2:00 PM→4:20 PMRyanairUntil Oct 23Boeing 737-800 · 2h 20mThu, Fri
3:15 PM→5:45 PMAir EuropaBoeing 737 MAX 8 · 2h 30mMon, Tue, Wed, Thu, Fri, Sun
4:35 PM→7:00 PMIberiaAirbus A321 · 2h 25mMon, Tue, Wed, Thu, Fri, Sun
5:30 PM→7:55 PMBrussels AirlinesAirbus A320neo · 2h 25mMon, Tue, Wed, Thu, Fri, Sun
8:10 PM→10:35 PMIberiaAirbus A320 · 2h 25mMon, Tue, Wed, Thu, Fri, Sun
8:55 PM→11:10 PMBrussels AirlinesAirbus A319 · 2h 15mThu, Fri

Schedules last checked Oct 1, 2026. Times are local.

Flying from Madrid to Brussels

Iberia flies most often, 20 times a week on the Airbus A320, Airbus A321 and CRJ 1000. Brussels Airlines flies 18 times a week on the Airbus A320neo, Airbus A319 and Airbus A320. Air Europa flies 12 times a week on the Boeing 737 MAX 8. Ryanair flies on Thursdays and Fridays with the Boeing 737-800.

Flights run every day except Saturdays, up to 11 a day. The first arrival in Brussels is at 8:50 AM and the last at 11:10 PM. The flight covers 818 miles, and scheduled flight times run from 2h 15m to 2h 30m.

Ryanair flies it until Oct 23.

Flying back, Brussels to Madrid has 63 nonstop flights a week.

Return flights

Brussels to MadridView

Find the cheapest day to fly from Madrid to Brussels.

Schedules as of Oct 9, 2026.