Nonstop flights from Rome to Brussels

4 airlines fly this route, with up to 8 flights a day.

FCORome Leonardo da Vinci International

729 mi · 50 flights a week

BRUBrussels

FCOBRU

When they leave

Rome time

6:40a9:00pFirst departure 6:40 AM, last 9:00 PM

Three in the morning, 6:40 AM to 10:10 AM, then two in the afternoon, 3:45 PM to 4:35 PM, then two in the evening, 6:10 PM to 9:00 PM.

Every flight

Earliest first

6:40 AM→8:50 AMeasyJetAirbus A319Daily
8:35 AM→10:45 AMITA AirwaysAirbus A220-300Mon, Tue, Wed, Thu, Sat, Sun
10:10 AM→12:25 PMBrussels AirlinesAirbus A320Mon, Tue, Wed, Thu, Fri, Sat
3:45 PM→5:55 PMITA AirwaysAirbus A321neoDaily
4:35 PM→6:50 PMRyanairUntil Oct 24, back Mar 28, 2027Boeing 737-800Mon, Tue, Thu, Fri, Sat, Sun
6:10 PM→8:20 PMBrussels AirlinesAirbus A320Daily
6:10 PM→8:20 PMeasyJetAirbus A319Daily
9:00 PM→11:15 PMBrussels AirlinesAirbus A319Mon, Thu, Fri, Sun

Schedules last checked Sep 19, 2026. Times are local.

Flying from Rome to Brussels

Brussels Airlines flies most often, 2 to 3 times a day on the Airbus A320 and Airbus A319. easyJet flies twice a day on the Airbus A319. ITA Airways flies 1 to 2 times a day on the Airbus A220-300 and Airbus A321neo. Ryanair flies 6 times a week on the Boeing 737-800.

Flights run every day of the week, from 6 on Wednesdays to 8 on Mondays and Thursdays. The first arrival in Brussels is at 8:50 AM and the last at 11:15 PM. The flight covers 729 miles.

Ryanair flies it until Oct 24 and is back on Mar 28, 2027.

Flying back, Brussels to Rome has 50 nonstop flights a week.

Return flights

Brussels to RomeView

Find the cheapest day to fly from Rome to Brussels.

Schedules as of Oct 9, 2026.