Nonstop flights from Houston to Panama City

Southwest Airlines flies this route 1 to 3 times a day.

HOUHouston William P. Hobby

569 mi · 10 flights a week

ECPPanama City Northwest Florida Beaches International

HOUECP

When they leave

Houston time

9:50a6:45pFirst departure 9:50 AM, last 6:45 PM

Two in the morning, 9:50 AM to 10:15 AM, then two in the afternoon, 1:40 PM to 2:05 PM, then three in the evening, 5:45 PM to 6:45 PM.

Every flight

Earliest first

9:50 AM→11:30 AMSouthwest AirlinesBoeing 737 MAX 8Mon, Sun
10:15 AM→12:00 PMSouthwest AirlinesBoeing 737-700Sat
1:40 PM→3:20 PMSouthwest AirlinesBoeing 737-700Thu, Fri
2:05 PM→3:45 PMSouthwest AirlinesBoeing 737Sat
5:45 PM→7:25 PMSouthwest AirlinesBoeing 737-700Sat
5:55 PM→7:35 PMSouthwest AirlinesBoeing 737 MAX 8Sun
6:45 PM→8:30 PMSouthwest AirlinesBoeing 737Tue, Wed

Schedules last checked Sep 19, 2026. Times are local.

Flying from Houston to Panama City

Southwest Airlines is the only airline flying nonstop from Houston to Panama City, 1 to 3 times a day on the Boeing 737-700, Boeing 737 and Boeing 737 MAX 8.

Flights run every day of the week, from 1 on Mondays, Tuesdays, Wednesdays, Thursdays and Fridays to 3 on Saturdays. The first arrival in Panama City is at 11:30 AM and the last at 8:30 PM. The flight covers 569 miles.

Flying back, Panama City to Houston has 7 nonstop flights a week. George Bush Intercontinental (IAH) also has nonstop flights to Panama City, 21 a week.