Nonstop flights from Charlotte to Panama City

American Airlines flies this route 3 to 4 times a day.

CLTCharlotte Douglas International

439 mi · 22 flights a week

ECPPanama City Northwest Florida Beaches International

CLTECP

When they leave

Charlotte time

10:25a10:00pFirst departure 10:25 AM, last 10:00 PM

One morning flight at 10:25 AM, then two in the afternoon, 1:05 PM to 4:29 PM, then one evening flight at 10:00 PM.

Every flight

Earliest first

10:25 AM→11:12 AMAmerican AirlinesCRJ 900Daily
1:05 PM→1:50 PMAmerican AirlinesCRJ 900Sun
4:29 PM→5:16 PMAmerican AirlinesCRJ 900Daily
10:00 PM→10:40 PMAmerican AirlinesCRJ 900Daily

Schedules last checked Sep 22, 2026. Times are local.

Flying from Charlotte to Panama City

American Airlines is the only airline flying nonstop from Charlotte to Panama City, 3 to 4 times a day on the CRJ 900.

Flights run every day of the week, 4 on Sundays and 3 on the other days. The first arrival in Panama City is at 11:12 AM and the last at 10:40 PM. The flight covers 439 miles.

Flying back, Panama City to Charlotte has 22 nonstop flights a week.

Return flights

Panama City to CharlotteView

More to Panama City

Find the cheapest day to fly from Charlotte to Panama City.

Schedules as of Oct 9, 2026.