Nonstop flights from Destin to Chicago
American Airlines flies this route 6 times a week, starting again Oct 10.
VPSDestin-Fort Walton Beach
797 mi · 6 flights a week
ORDChicago O'Hare International
When they leave
Destin time11:28a11:28aDeparts 11:28 AM
One departure, at 11:28 AM.
Every flight
Earliest first
Schedules last checked Sep 22, 2026. Times are local.
Flying from Destin to Chicago
American Airlines is the only airline flying nonstop from Destin to Chicago, 6 times a week on the Embraer 175.
Flights run every day except Fridays. The flight covers 797 miles.
Flying back, Chicago to Destin has 6 nonstop flights a week.
Return flights
Every Chicago airport
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Find the cheapest day to fly from Destin to Chicago.
Schedules as of Oct 9, 2026.