Nonstop flights from San Diego to San Luis Obispo
Alaska Airlines flies this route twice a day.
SANSan Diego International
262 mi · 14 flights a week
SBPSan Luis Obispo SLO County
When they leave
San Diego time4:05p10:28pFirst departure 4:05 PM, last 10:28 PM
One afternoon flight at 4:05 PM, then one evening flight at 10:28 PM.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from San Diego to San Luis Obispo
Alaska Airlines is the only airline flying nonstop from San Diego to San Luis Obispo, twice a day on the Embraer 175.
The first arrival in San Luis Obispo is at 5:17 PM and the last at 11:40 PM. The flight covers 262 miles.
Flying back, San Luis Obispo to San Diego has 14 nonstop flights a week.
Return flights
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Schedules as of Oct 9, 2026.