Nonstop flights from San Diego to Indianapolis
Southwest Airlines flies this route daily.
SANSan Diego International
1,779 mi · 7 flights a week
INDIndianapolis International
When they leave
San Diego time10:15a1:10pFirst departure 10:15 AM, last 1:10 PM
Three in the morning, 10:15 AM to 11:15 AM, then one afternoon flight at 1:10 PM.
Every flight
Earliest first
Schedules last checked Sep 20, 2026. Times are local.
Flying from San Diego to Indianapolis
Southwest Airlines is the only airline flying nonstop from San Diego to Indianapolis, daily on the Boeing 737 MAX 8.
The first arrival in Indianapolis is at 5:10 PM and the last at 8:10 PM. The flight covers 1,779 miles.
Flying back, Indianapolis to San Diego has 7 nonstop flights a week.
Return flights
More from San Diego
Find the cheapest day to fly from San Diego to Indianapolis.
Schedules as of Oct 9, 2026.