Nonstop flights from Roanoke to Chicago

2 airlines fly this route, with up to 5 flights a day.

ROARoanoke-Blacksburg

531 mi · 29 flights a week

ORDChicago O'Hare International

ROAORD

When they leave

Roanoke time

6:00a5:52pFirst departure 6:00 AM, last 5:52 PM

Three in the morning, 6:00 AM to 10:47 AM, then two in the evening, 5:35 PM to 5:52 PM.

Every flight

Earliest first

6:00 AM→7:14 AMAmerican AirlinesEmbraer 175Mon, Tue, Sun
6:00 AM→7:15 AMAmerican AirlinesEmbraer 175Wed
6:40 AM→7:53 AMUnited AirlinesEmbraer 175Daily
10:47 AM→11:57 AMUnited AirlinesCRJ 700Daily
5:35 PM→6:58 PMAmerican AirlinesEmbraer 175Wed, Thu, Fri, Sat
5:52 PM→7:05 PMUnited AirlinesEmbraer 175Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Roanoke to Chicago

United Airlines flies most often, 3 times a day on the Embraer 175 and CRJ 700. American Airlines flies 1 to 2 times a day on the Embraer 175.

Flights run every day of the week, 5 on Wednesdays and 4 on the other days. The first arrival in Chicago is at 7:14 AM and the last at 7:05 PM. The flight covers 531 miles.

Flying back, Chicago to Roanoke has 28 nonstop flights a week.

Return flights

Chicago to RoanokeView

More to Chicago

Find the cheapest day to fly from Roanoke to Chicago.

Schedules as of Oct 9, 2026.